中国组织工程研究与临床康复2011，Vol.15Issue(7)：1255-1258,4.DOI:10.3969/j.issn.1673-8225.2011.07.026
组织工程肺的细胞源及支撑架
Cell source and support scaffolding of tissue-engineered lung
王磊 1陈寅 1钟竑
1
作者信息
- 1. 上海交通大学医学院新华医院心胸外科,上海市,200092
- 折叠
摘要
Abstract
BACKGROUND: Although there was slow progress in the engineering of the lung, new functional replacement lung tissue can be generated through tissue engineering in the use of stem or progenitor cells and related support scaffolding under certain condition.The research about the cell source and support scaffolding of a tissue-engineered lung has gained homologous progress.OBJECTIVE: To review recent advance on the development of cell source and support scaffolding in the tissue-engineered lung research.METHODS: A computer-based online search of China Journal Full-text Database and PubMed was performed for articles and reviews in Chinese and English from January 1990 to January 2009. The key words were "tissue-engineered lung, cell source,support scaffolding". A total of 89 articles were retrieved, and screened following reading titles and abstracts. Literatures about cell source and support scaffolding in the tissue-engineered lung research were included. Repetitive articles with poor quality were excluded. Finally, 33 literatures were included.RESULTS AND CONCLUTION: Because lung tissues have a complex three-dimensional structure and little capacity of regeneration, it is difficult to cure for lung diseases. At present, it is known that the new functional replacement lung tissue can be generated through tissue engineering. This is a promised therapeutic tool, but it still is the basal research stage. With the development of the cell source and support scaffolding of a tissue-engineered lung, there will be more and more new discovery.Tissue-engineered lung research will have a broad prospect in the clinical application.关键词
组织工程肺/细胞源/支撑架/肺移植/研究进展/综述文献分类
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王磊,陈寅,钟竑
..组织工程肺的细胞源及支撑架[J].中国组织工程研究与临床康复,2011,15(7):1255-1258,4.
