中国组织工程研究与临床康复2011，Vol.15Issue(6)：1137-1140,4.DOI:10.3969/j.issn.1673-8225.2011.06.042
脐血间充质干细胞移植治疗低血糖昏迷1例
Umbilical cord blood mesenchymal stem cells transplantation for treating hypoglycemic coma in one case
李平 1周瑞 1晏小琼 1余勇飞 1阮清源1
作者信息
- 1. 湖北省新华医院脑科中心神经内科,湖北省武汉市,430015
- 折叠
摘要
Abstract
BACKGROUND: Adult stem cells can differentiate into all kinds of cell type. Under special conditions, adult stem cells can differentiate into osteoblasts, chond rocytes, adipocytes, muscle cells and neural cells to replace and to repair damaged tissues and cells, to achieve functional recovery purposes.OBJECTIVE: To observe the effect of umbilical cord blood mesenchymal stem cells (UCB-MSCs) therapy in hypoglycemic coma combined with hypoxic ischemic encephalopathy.METHODS: One case of hypoglycemic coma combined with hypoxic ischemic encephalopathy and pulmonary infection was admitted. This patient received a combined treatment, including anti-free radical, nerve-nurturing, consciousness-regaining,anti-infective therapy, rehabilitation and physiotherapy. At the same time, we also gave him the UCB-MSCs therapy by intravenous infusion. The recovery of consciousness, electroencephalogram, activity of daily living and follow-up results were observed during hospital stay.RESULTS AND CONCLUSION: One month later, the patient's motor and cognitive function recovered better.Electroencephalogram was rechecked. The a wave was observed. The activity of daily living scored 50 points. Seventy days later,follow-up showed that no adverse reaction was detectable, which suggested that stem cell therapy was safe in short period.These indicated that UCB-MSCs for hypoglycemic coma combined with hypoxic ischemic encephalopathy are safe and effective.关键词
低血糖昏迷/缺氧缺血性脑病/脐血间充质干细胞/脑电图/日常生活能力分类
医药卫生引用本文复制引用
李平,周瑞,晏小琼,余勇飞,阮清源..脐血间充质干细胞移植治疗低血糖昏迷1例[J].中国组织工程研究与临床康复,2011,15(6):1137-1140,4.
