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山药苡仁健脾粉及其拆方的药理作用研究

牟正 薛莉君 王红利 张芬 祝慧凤

中国药房2011,Vol.22Issue(11):964-967,4.
中国药房2011,Vol.22Issue(11):964-967,4.

山药苡仁健脾粉及其拆方的药理作用研究

Study on Pharmacological Effect of Shanyao Yiren Jianpi Powder and Its Disassembled Prescription

牟正 1薛莉君 1王红利 1张芬 1祝慧凤1

作者信息

  • 1. 西南大学药学院暨中医药学院,重庆市,400715
  • 折叠

摘要

Abstract

OBJECTIVE: To study pharmacological effects of Shanyao yiren jianpi powder and its disassembled prescription.METHODS: Effect of Shanyao yiren jianpi powder on the immunologic function regulation of mice was observed by cyclophosphamide induced immunodepression test and carbon clearance test. Small intestinal propulsive motion experiment was adopted to evaluate the effect of Shanyao yiren jianpi powder and its disassembled prescription on intestinal motion. The antifatigue effect of Shanyao yiren jianpi powder and its disassembled prescription was observed by rotarod test. Hyperglycemia model was induced by alloxan, and effect of Shanyao yiren jianpi powder and its disassembled prescription on model mice were observed. RESULTS: Dioscorea opposite powder, Coix lacryma-jobi powder and Shanyao yiren jianpi powder improved immunologic function of mice, increased carbon clearance rate, inhibited leukocytopenia induced by CTX, and resist fatijue. D. opposite powder and Shanyao yiren powder improved intestinal motion and lower blood glucose while effect of C. lacryma-jobi powder was not obvious. CONCLUSION: Shanyao yiren jianpi powder shows several health functions, such as improving intestinal motion, regulating immunity, resisting fatigue and lowering blood glucose. It has value developed further.

关键词

山药苡仁健脾粉/拆方/碳廓清/环磷酰胺/胸腺指数/脾脏指数/小肠推进率/抗疲劳/降糖

分类

医药卫生

引用本文复制引用

牟正,薛莉君,王红利,张芬,祝慧凤..山药苡仁健脾粉及其拆方的药理作用研究[J].中国药房,2011,22(11):964-967,4.

基金项目

西南大学博士基金项目(104290-20710906) (104290-20710906)

中国药房

OACSCDCSTPCD

1001-0408

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