重庆医学2011，Vol.40Issue(9)：838-839,842,3.DOI:10.3969/j.issn.1671-8348.2011.09.003
安氏Ⅱ2类错(牙合)家庭聚集性与遗传度研究
Familial aggregation and heritability of class Ⅱ 2 malocclusion
摘要
Abstract
Objective To explore the role of genetic factor in class Ⅱ 2 malocclusion. Methods 276 pedigrees,including 126 class Ⅱ 2 malocclusion pedigrees and 150 control pedigrees, were investigated in Chongqing area. Familial aggregation was evaluated by binominal analysis. Results The prevalence rate of class Ⅱ 2 malocclusion in first-degree relatives was 25.37％, significantly higher than 6.06％ of control pedigrees. The results from binominal distribution analysis showed that actual frequency of class Ⅱ 2 cases were significantly higher than that of theoretical frequency(ρ＜0.05), which indicated that there was significant familial aggregation in the occurrence of class Ⅱ 2 malocclusion. The estimated value of control pedigrees was 92.26 ％. Conclusion Class Ⅱ 2 mal occlusion shows significantly familial aggregation. Genetic factors play an important role in the incidence of class Ⅱ 2 malocclusion.关键词
错(牙合)/安氏Ⅱ类/家庭聚集性/遗传度Key words
malocclusion, angle class Ⅱ/ familial aggregation/ heritability引用本文复制引用
陈允嘉,王豫蓉,邹林洪,李艳,郑雷蕾,吴艳,秘双燕,吴增波,王强..安氏Ⅱ2类错(牙合)家庭聚集性与遗传度研究[J].重庆医学,2011,40(9):838-839,842,3.基金项目
重庆市卫生局重点课题资助项目(2009-1-32). （2009-1-32）
