北京生物医学工程2011，Vol.30Issue(2)：215-220,6.DOI:10.3969/j.issn.1002-3208.2011.02.24.
Caveolae及其蛋白家族的生物学结构和功能的研究现状
Biological Structure and Function of Caveolae and Protein Family
摘要
Abstract
Caveolae which is about 50 - l00nm various invaginations exists on the surface of cell plasma membrane. Caveolae enriches the most signal transduction proteins and is responsible for many biological functions. It is the center of cell signal processing for carring the signal transduction inhibitor. Caveolin are Caveolae' s characteristic proteins, which can fix the signal molecules by forming scaffold when the cell in a steady state or the signal behavior leading by ligand. As the permanent structure on the plasma membrane,the research on physiological function of caveolae and caveolin are getting more and more attention , especially in signal transduction , cholesterol transport, tumor suppression, muscle cell synthesis and so on. Based on recent domestic and foreign studies on caveolae and caveolin,we concluded the progress of caveolae with multiple perspectives.关键词
胞膜窖/窖蛋白/结构功能/信号转导分类
医药卫生引用本文复制引用
张勤勤,孙润广,李连启..Caveolae及其蛋白家族的生物学结构和功能的研究现状[J].北京生物医学工程,2011,30(2):215-220,6.基金项目
国家自然科学基金(20772077)和教育部科学技术研究重点项目(104167)资助 （20772077）
