重庆医学2011,Vol.40Issue(11):1070-1072,3.DOI:10.3969/j.issn.1671-8348.2011.11.012
慢性肺源性心脏病急性加重期患者红细胞的血液流变学和生物力学特性研究
Erythrocyte hemorheology and biomechanics properties in acute phase patients with chronic pulmonary heart disease
摘要
Abstract
Objective To compare erythrocyte hemorheology and biomechanics properties in acute phase patients with chronicpulmonary heart disease with healthy controls.Methods In the venous blood 40 acute phase patients with chronic pulmonary heartdisease and 38 healthy controls,the erythrocyte hemorheology parameter, modulus of elasticity,viscous coefficient,the ratio of sur-face area/volume were determined.Results (1)The blood of acute phase patients with chronic pulmonary heart disease was in thehyperviscosity state.The blood viscosity, plasma viscosity, hematocrit, aggregation indexes, erythrocyte sedimentation were highercompared with healthy controls, but erythrocyte deformability index was decreased.(2)In the acute phase patients with chronic pul-monary heart disease,the ratio of erythrocyte surface/volume was decreased, membrane elastic modulus and viscous coefficients erythrocytes were increased.Conclusion The decrease of erythrocyte deformability of the acute phase patients with chronic pulmo-nary heart disease maybe result from the abnormal of geometry and membrane viscoelastic properties.These abnormal will be unfa-vorable to erythrocyte deformability.关键词
肺心病/红细胞/血液流变学/红细胞变形性引用本文复制引用
张燕,黄勇..慢性肺源性心脏病急性加重期患者红细胞的血液流变学和生物力学特性研究[J].重庆医学,2011,40(11):1070-1072,3.