高等学校化学学报2011，Vol.32Issue(3)：688-693,6.
量子点荧光探针检测抗坏血酸
Detection of Ascorbic Acid by Quantum Fluorescence Probe
摘要
Abstract
CdTe quantum dots of highly fluorescent was prepared in aqueous solution with mercaptopropanoic acid(MPA) as stabilizer. The fluorescence of the CdTe QDs was significantly quenched with blue shift by the addition of Mn2+ due to the change of surface structure and chemical properties of the QDs. The fluorescence recovery was afterwards achieved in the presence of a small amount of ascorbic acid, which provided a novel QD-based tutu-on fluorescent probe for the detection of ascorbic acid. When using QDs of 1.91 nm in size and a concentration of 1.67 μmoL/L in the presence of 0.25 mmoL/L Mn2+ , the recovered fluorescence was linearly related with the ascorbic acid concentration within 0.25—16 μmol/L, with a detection limit of 36 nmol/L.The relative standard deviation was derived to be 2.6％ at 10 μmol/L of ascorbic acid( n = 11 ). The probe has been applied for the detection of ascorbic acid in Vc tablets and human whole blood samples.关键词
CdTe量子点/荧光探针/抗坏血酸Key words
CdTe quantum dot/ Fluorescent probe/ Ascorbic acid分类
化学化工引用本文复制引用
张立佩,胡博,王建华..量子点荧光探针检测抗坏血酸[J].高等学校化学学报,2011,32(3):688-693,6.基金项目
国家自然科学基金(批准号:20805004)、国家杰出青年科学基金(批准号:20725517)和中央高校基本科研业务费(批准号:N090105001,N090605001,N090405004,N100305003,N100305004,N100605002)资助. （批准号:20805004）
