疑难病杂志2011，Vol.10Issue(4)：247-250,4.DOI:10.3969/j.issn.1671-6450.2011.04.001
血清游离三碘甲状腺原氨酸及脑钠肽水平在慢性心力衰竭患者长期预后中的价值
The value of serum free triiodothyronine and BNP in long term prognostic of patients with chronic heart failure
摘要
Abstract
Objective To determine the serum free triiodothyronine( FT3 ) and brain natriuretic peptide( BNP )levels in patients with chronic heart failure, and to explore the value of them in the prognostic of chronic heart failure. Methods Totally 334 consecutive patients who were admitted to our clinic from September 2005 to September 2009 with the diagnosis of chronic heart failure. The general materials, blood biochemical, and echocardiographic results, medication, and the major cardiovascular events( MCEs )were collected throw phone or outpatient follow up. The relationship between FT3 and BNP was analyzed. Results During the follow up period, 92 patients ( 27.5％ ) experienced MCEs. Mean level of BNP was higher than that without major cardiac events( P ＜ 0.01 ), while the level of FT3 was lower( P ＜ 0.01 ). A significant negative correlation was found between the levels of FT3 and BNP( r＝ - 0.22, P ＜ 0.01 ). Multiple regression analysis showed that the predictive cutoff values were less than 2.12 ng/L for FT3 and more than 686 ng/L for BNP. Besides, the multivariate analysis showed that the independence predictors included age, serum FT3 level and BNP level. Conclusion It demonstrated that the higher level of BNP and lower level of serum FT3 may be predictive markers for worse outcomes.关键词
心力衰竭/预后/多变量分析/游离T3/脑钠肽引用本文复制引用
胡华兵,杨波..血清游离三碘甲状腺原氨酸及脑钠肽水平在慢性心力衰竭患者长期预后中的价值[J].疑难病杂志,2011,10(4):247-250,4.
