摘要
Abstract
Diabetes, especially T2DM, spreading globally, has become a chronic non - communicable disease threatening human beings' health. Its macrovascular, microvascular and neurologic complications are great threats to patients' life and quality of life, giving a heavy financial burden to the social, families and patients themselves. In addition, cognitive impairment is one of the chronic complications of diabetes. T2DM cognitive impairment is related not only to vascular risk factors but to diabetes itself such as blood glucose control, duration of diabetes and drug treatment, and to direct or indirect effects of metabolic disorders. This paper reviews the possible reasons for diabetes combined with cognitive impairment, such as hyperglycosemia, hypoglycemia, lipid metabolism disorders, hyperhomocysteinaemia, advanced glycosylation end products ( AGEs ), insulin, neuropathy, etc. , to provide basis for clinicians to diagnose and treat diabetes combined with cognitive impairment.关键词
糖尿病/认知障碍/高血糖症/低血糖症/糖基化终产物/高同型半胱氨酸血症/脂代谢障碍分类
医药卫生