中国全科医学2011，Vol.14Issue(9)：940-942,3.
低钠血症对失代偿期肝硬化患者的预后分析
Prognostic Value of Hyponatremia in Patients with Decompensated Cirrhosis
狄连君 1赵逵 1李红平 1陈浩2
作者信息
- 1. 563003贵州省遵义市,遵义医学院附属医院消化内科
- 2. 563003贵州省遵义市,遵义医学院附属医院急诊科
- 折叠
摘要
Abstract
Objective To explore the value of hyponatremia in predicting the outcomes of patients with decompensated cirrhosis. Methods Totally 61 patients with decompensated cirrhosis who were treated in our hospital from 2000 to 2009 were enrolled in this study. Based on their outcomes, they were divided into death group ( n = 19 ) and survival group ( n = 42 ). The serum levels of sodium, total bilirubin, and creatinine, prothrombin time, MELD score, and Child-Pugh score were analyzed and compared between these two groups. Results Compared with the survival group, the serum levels of total bilirubin and creatinine, prothrombin time, MELD score, and Child-Pugh score were significantly higher in death group, while the serum sodium level significantly decreased ( P ＜ 0. 05 ). The hyponatremia showed significant negative correlations with Child-Pugh score and MELD score ( r = -0. 527 , P ＜0. 01; r = - 0. 419, P ＜ 0. 01 ). MELD score showed significant positive correlations with Child - Pugh score ( r = 0. 754, P ＜ 0. 01 ). COX regression analysis showed both hyponatremia and MELD score were the independent predictors of death among decompensated cirrhotic patients ( P = 0. 000, P = 0. 015 ). Conclusion Hyponatremia is a good parameter for predicting the prognosis of decompensated cirrhotic patients.关键词
肝硬化/低钠血症/MELD评分/Child-Pugh评分/预后分类
医药卫生引用本文复制引用
狄连君,赵逵,李红平,陈浩..低钠血症对失代偿期肝硬化患者的预后分析[J].中国全科医学,2011,14(9):940-942,3.
