中国全科医学2011,Vol.14Issue(2):151-155,5.
颅内动脉瘤破裂致蛛网膜下腔出血预后不良的危险因素研究
Risk Factors of Poor Prognosis of Subarachnoid Hemorrhage Caused by Ruptured Intracranial Aneurysms
呼铁民 1韩凤伟 1王维兴 1马志君 1张继伟 1田甜 1于淼 1王昆鹏1
作者信息
- 1. 067000,河北省承德市,承德医学院附属医院神经外科
- 折叠
摘要
Abstract
Objective To explore the risk factors of poor prognosis of suharachnoid hemorrhage ( SAH ) caused by ruptured intracranial aneurysms. Methods A retrospective analysis was carried out in 359 patients with SAH caused by ruptured intracranial aneurysms who were admitted to our neurosurgery department from January 2007 to August 2009. Two hundred sixty eight of 288 patients who underwent microsurgical operation of intracranial aneurysms met the inclusion criteria and were enrolled in this study. Glasgow outcome scale ( GOS ) was used to evaluate patients' prognoses. The patients were divided, according to different prognoses, into groups poor prognosis ( group A, GOS≤3 ) and good prognosis ( group B, GOS = 4 ~ 5 ). The prognoses were evaluated by 1 - month , 3 - month, 1 - year GOSs. Results Excess alcohol consumption, perioperative hyperglycemia. Ⅳ ~ Ⅴ Hent - Hess grading, grade Ⅳ ~ Ⅴ of subarachnoid hemorrhage rating ( CT Fisher grading ) and middle - or late - phase operations on patients with Ⅳ ~ Ⅴ Hent - Hess grade were clinical factors with significance causing poor prognoses in patients with ruptured - intracranial - aneurysm - induced SAH ( P < 0. 05 ). Hypertension, hyperlipidemia, diabetes, smoking, family history of aneurysms and operative timing of patients with Ⅰ ~ Ⅲ Hunt - Hess grading were not correlated with SAH prognoses , the difference was not significant ( P > 0. 05 ). Conclusion Excess alcohol consumption, perioperative hyperglycemia, Ⅳ ~ Ⅴ Hent - Hess grading, Ⅳ ~ Ⅴ CT Fisher grading, multiple aneurysms and postope.rative rebleeding, cerebral vasospasm are risk factors leading to poor prognoses in patients with ruptured - intracranial - aneurysm - induced SAH.关键词
颅内动脉瘤/蛛网膜下腔出血/预后/危险因素分类
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呼铁民,韩凤伟,王维兴,马志君,张继伟,田甜,于淼,王昆鹏..颅内动脉瘤破裂致蛛网膜下腔出血预后不良的危险因素研究[J].中国全科医学,2011,14(2):151-155,5.