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干细胞移植在心肌梗死治疗中的应用进展

胡依民

中国全科医学2011,Vol.14Issue(2):221-223,3.
中国全科医学2011,Vol.14Issue(2):221-223,3.

干细胞移植在心肌梗死治疗中的应用进展

Application of Stem Cell Transplantation in Myocardial Infarction

胡依民1

作者信息

  • 1. 300020,天津市,中国医学科学院中国协和医科大学血液学研究所
  • 折叠

摘要

Abstract

In the pathophysiological process of myocardial infarction ( MI ), myocardial cells are found dead or ap-optosis with reduction in the number of myocardial cells. After MI occurs, the survival myocardial cells become compensatory hypertrophy and ventricles remodeled, which leads to decreased heart function. Current treatment can only narrow the extent of MI, recover blood supply in the survival ischemic myocardium and delay left ventricular remodeling to improve prognoses, rather than repair fundamentally the necrotic myocardial tissues. The latest animal experiments and clinical studies show that stem cell transplantation into the necrotic area of myocardial cells can effectively complement myocardial cells and contribute to cardiac function improvement. Stem cell transplantation, probably the most promising treatment for MI, myocardial regeneration, prevention of left ventricular remodeling and heart failure, is easy to perform, having wide beneficiaries and a broad application prospect.

关键词

干细胞移植/心肌梗死/心室重构

分类

医药卫生

引用本文复制引用

胡依民..干细胞移植在心肌梗死治疗中的应用进展[J].中国全科医学,2011,14(2):221-223,3.

中国全科医学

OA北大核心CSTPCD

1007-9572

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