中华医学杂志（英文版）2011，Vol.124Issue(6)：935-938,4.DOI:10.3760/cma.j.issn.0366-6999.2011.06.024
Is islet transplantation ready for widespread use in diabetes?
Is islet transplantation ready for widespread use in diabetes?
摘要
Abstract
Up till 2000 when Edmonton group introduced islet transplant procedure in conjunction with a novel glucocorticoid-free immunosuppressive regimen rendering 100％ (n=7) of patients with type 1 diabetes insulin-independent for at least 1 year, islet transplant was taken into the clinic. Although significant progress in clinical islet transplant has occurred during recent years, challenges remain, including shortage of available donor organs, technical aspects of islet preparation and transplantation, immunological rejection post-transplant, unclear long-term outcomes of islet transplantation. Special attention is given to current limitation in islet transplantation together with new possible strategies that raise expectations for the widespread use of islet transplantation in the future.关键词
islet transplantation/diabetes mellitus/immunosuppressionKey words
islet transplantation/diabetes mellitus/immunosuppression引用本文复制引用
WANG Jin,WANG Qing-hua,XIA Tian ,TAN Jian-ming..Is islet transplantation ready for widespread use in diabetes?[J].中华医学杂志（英文版）,2011,124(6):935-938,4.基金项目
This study was supported by grants from the Major Program of Natural Science Foundation of Fujian Province (No.2009Y4001 and No.2008J1006). （No.2009Y4001 and No.2008J1006）
