神经损伤与功能重建2011，Vol.6Issue(1)：32-35,4.DOI:10.3870/sjsscj.2011.01.008
急性脑梗死生化标志物的变化及意义
Dynamic Changes of Biochemical Markers in Patients with Acute Cerebral Infarction
摘要
Abstract
Objective: To explore the dynamic changes of thrombus precursor protein (TpP) ,myelin basic protein (MBP), and S-100 protein (S-100) in patients with acute cerebral infarction (ACI) and the clinical significances. Methods: The plasma levels of TpP,MBP, S-100 in 98 patients with ACI at 6, 12, 24 hours after disease onset and in 98 control subjects were deter mined by enzyme linked immunosorbent assay. Results: Compared with the control subjects, the concentration of TpP in plasma of ACI patients began to increase significantly 6 hours after onset, peaked at hour 12 and kept a high level for 24 hours; MBP in plasma of ACI patients showed no obviously increase 12 hours after onset but increased significantly 24 hours later (P＜0.01);S-100 showed no increase throughout all the time points investigated. Conclusion: The levels of TpP, MBP, and S-100 in patients alter in the duration of acute cerebral infarction.关键词
急性脑梗死/血栓前体蛋白/S-100 蛋白/髓鞘碱性蛋白Key words
acute cerebral infarction/ thrombus precursor protein/ S-100 protein/ myelinbasic protein分类
医药卫生引用本文复制引用
王喜丰,冯永钦,代泉玉,曹一山,汪万国,付群芳..急性脑梗死生化标志物的变化及意义[J].神经损伤与功能重建,2011,6(1):32-35,4.基金项目
宜昌市科技局计划项目(宜科发)2009 12号 （宜科发）
