| 注册
首页|期刊导航|重庆医学|参麦对大鼠失血性休克早期炎症反应的抑制作用研究

参麦对大鼠失血性休克早期炎症反应的抑制作用研究

赵明 蒋鹏 焦志军 周峰

重庆医学2011,Vol.40Issue(1):12-13,2.
重庆医学2011,Vol.40Issue(1):12-13,2.DOI:10.3969/j.issn.1671-8348.2011.01.005

参麦对大鼠失血性休克早期炎症反应的抑制作用研究

The inhibited effect of treatment of shenmai on inflammatory mediators in early phase of hemorrhagic shock

赵明 1蒋鹏 1焦志军 1周峰1

作者信息

  • 1. 江苏大学附属医院,镇江,212001
  • 折叠

摘要

Abstract

Objective To investigate the effect of shenmai(SM) on serum levels of interleukin-lβ(IL-1β),IL-6,tumor necrosis factors(TNF-α),malondialdchyde(MDA) ,superoxide dismutase(SOD) after hemorrhagic shock in rats. Methods Thirty rats were selected and divided into three group randomly(n= 10),the control group(A),hemorrhagic group(B) and hemorrhagic +SM group (C). The serum levels of IL-1β, IL-6,TNF-α, MDA and SOD were determined by ELISA or chemical reaction method. Results Serum levels of IL-1β,IL-6 ,TNF-α, MDA,in group B were highter than those in group A,and the SOD level of group B was lower than those in group A(P<0.01). Serum levels of IL-1β,IL-6,TNF-α and MDA in group C were lower than those in group B,and the levels of SOD of group C were higher than those in group B( P<0.05 ). Conclusion Shenmai can inhibit the expression of inflammatory factors,and stimulate the action of SOD after hemo rrhagic shock.

关键词

休克,出血性/炎症介导素类/参麦

Key words

shock/ hemorrhagic/ inflammation mediators / shenmai

引用本文复制引用

赵明,蒋鹏,焦志军,周峰..参麦对大鼠失血性休克早期炎症反应的抑制作用研究[J].重庆医学,2011,40(1):12-13,2.

重庆医学

OA北大核心CSCDCSTPCD

1671-8348

访问量3
|
下载量0
段落导航相关论文