重庆医学2011，Vol.40Issue(1)：17-19,3.DOI:10.3969/j.issn.1671-8348.2011.01.007
随机单盲对照研究观察托特罗定治疗留置尿管相关膀胱不适的疗效
Efficacy of tolterodine for prevention of catheter-related bladder discomfort: a randomized,placelbo-controlled,single-blind study
何云锋 1吴小候 1唐伟 1陈在贤 1王德林 1尹志康 1蒲军 1陈刚 1张尧1
作者信息
- 1. 重庆医科大学附属第一医院泌尿外科,400016
- 折叠
摘要
Abstract
Objective To evaluate the efficacy of tolterodine for prevention of catheterrelated bladder discomfort. Methods We used tolterodine or placebo to prevent the bladder discomfort caused by the indwelling catheter from Oct. 2005 to Aug. 2010,the patient took tolterodine 2 mg twice daily or placebo 2 mg twice daily orally,from indwelling catheter to removal of the catheter. The groups included: operation on urethra group, transurethral resection of prostate group, transurethral resection of bladder tumor group,operation of ureteroscope group,operation of percutaneous nephroscope group and operation without intracavitary treatment group. Results In operation on urethra group, 1 of 36 patients had bladder discomfort treated with tolterodine,7 of 27 patients had bladder discomfort treated with placebo. In transurethral resection of prostate group,7 of 164 patients had bladder discomfort treated with tolterodine,43 of 107 patients had bladder discomfort treated with placebo. In transurethral resection of bladder tumor group,0 of 34 patients had bladder discomfort treated with tolterodine,9 of 42 patients had bladder discomfort treated with placebo. In operation of ureteroscope group, 9 of 217 patients had bladder discomfort treated with tolterodine,41 of 146 patients had bladder discomfort treated with placebo. In operation of pcrcutaneous nephroscope group,2 of 72 patients had bladder discomfort treated with tolterodine,25 of 95 patients had bladder discomfort treated with placebo. In operation without intracavitary treatment group, 4 of 47 patients had bladder discomfort treated with tolterodinc, 10 of 41 patients had bladder discomfort treated with placebo. Conclusion The toltcrodine therapy for patients with bladder discomfort caused by the indwelling catheter is effective.关键词
膀胱/托特罗定/留置尿管Key words
bladder / tolterodine/ indwelling catheter引用本文复制引用
何云锋,吴小候,唐伟,陈在贤,王德林,尹志康,蒲军,陈刚,张尧..随机单盲对照研究观察托特罗定治疗留置尿管相关膀胱不适的疗效[J].重庆医学,2011,40(1):17-19,3.
