临床误诊误治2011，Vol.24Issue(1)：15-16,2.
老年高血压病患者厄贝沙坦时辰化用药血压晨峰的变化分析
Effects of Chronotherapy on Morning Blood Pressure Surge in Elderly Patients with Hypertension
摘要
Abstract
Objective To investigate the influence of irbesartan taken before bedtime on morning blood pressure surge in elderly patients with essential hypertension.Methods 112 patients with elderly hypertension were selectd at outpatient service and in - patient department from January 1st, 2008 to August 31,2009.According to 24 h ambulatory blood pressure monitoring profiles, the study used morning blood pressure surge patients 112 cases,observed blood pressure and morning blood pressure surge after irbesartan taken before bedtime.Results Before irbesartan treatment, the average 24 h ambulatory systole presses, diastolic pressure and the morning blood pressure surge was ( 140.1 ± 12.7 ) mmHg, ( 85.3 ± 8.8 ) mmHg and (45.6 ± 10.8 )mmHg respectively, After irbesartan treatment, the average 24 h ambulatory systole presses, diastolic pressure and the morning blood pressure surge decreased to (129.5 ± 11.8 )mmHg, (74.2 ± I0.3 )mmHg and( 21.2 ±4.1 )mmHg,There was significant difference between before and after the treatment (P ＜ 0.01, P ＜ 0.05 ).The achievement ratio of 24 h ambulatory blood pressure was 84.5％.The morning blood pressure surge was depressed evidently( P ＜0.01 ), The achievement tatio of the morning blood pressure surge was 96.4％.Conclusion lrbesartan effectively reduce blood pressure and the peak morning blood pressure and improve achievement ratio of blood pressure.关键词
老年人/高血压/厄贝沙坦/药物疗法Key words
Aged/ Hypertension/ irbesartan/ Drug therapy分类
医药卫生引用本文复制引用
郭旭梅,马凤云,郭惠平..老年高血压病患者厄贝沙坦时辰化用药血压晨峰的变化分析[J].临床误诊误治,2011,24(1):15-16,2.
