临床输血与检验2011，Vol.13Issue(1)：1-4,4.DOI:10.3969/j.issn.1671-2587.2011.01.001
影响库存血运氧能力的指标分析
Analysis of Factors Affecting the Ability of Banked Blood to Transport Oxygen
摘要
Abstract
Objective The purpose of this study is to analyze the changing of factors affecting the ability of banked blood to transport oxygen after storage for different time.These factors mainly include the concentration of electrolyte,blood-gas, the RBC deformability, and nitric oxide (NO).Methods The concentration of electrolyte, blood-gas, and pH value were analyzed by the biochemical analyzer and the blood-gas analyzer.The RBC deformability was analyzed by the RBC deformability analyzer equipped with the laser diffraction.The total concentration of NO (NO2-+NOa-) was analyzed by the Griess essay.Results The concentration of K+ was increased from approximately 3 mmol/L to 24 mmol/L after storage of blood (P＜0.001).However, the concentration of Na+ was decreased from approximately 152 mmol/L to 133 mmol/L (P＜0.001).In addition, the concentration of Ca2+ or C1- remained constant with the prolonging of storage time.In addition, the pH value of blood after storage for 35 days was decreased to 6.449.The partial pressure of oxygen and the degree of oxygen saturation were increased during the storage period (P＜0.05).The RBC deformability was decreased after storage for two weeks (P＜0.001).The levels of nitric oxide remained constant with the prolonging of the storage time.Conclusion The factors including electrolyte, blood-gas, and RBC deformability are changing in banked blood with the prolonging of the storage time.The level of nitric oxide remains constant and can not indirectly reflect the real level of S-nitrosohemoglobin (SNO-Hb).关键词
库存血/电解质/RBC变形性/一氧化氮Key words
Banked blood/ Electrolyte/ RBC deformability/ Nitric oxide分类
医药卫生引用本文复制引用
冯双利,卓海龙,陈民才,杜为,王全立..影响库存血运氧能力的指标分析[J].临床输血与检验,2011,13(1):1-4,4.基金项目
本课题受国家自然科学基金(No.30971200)资助 （No.30971200）
