临床口腔医学杂志2011，Vol.27Issue(1)：5-7,3.DOI:10.3969/j.issn.1003-1634.2011.01.002
慢性牙周炎与口腔幽门螺杆菌的相关性研究
Correlativity of the chronic periodontitis with helicobacter pylori infection.
摘要
Abstract
Objective: To investigate the relationship between Helicobacter pylori (Hp) and periodontitis. Method: A polymerase chain reaction (PCR) assay with oligonucleotide primers homologous to a portion of the u-rease C and cytotoxinassociated gene A (cagA) of Hpwas used to test for the presence of Hpin dental plaque.Thirty-seven patients with periodontitis and 38 healthy persons were studied to compare the results of the two Groups. Result:In the periodontitis group,64.8 ％ f the tested samples was ureasc gene positive, and 32.4 ％ was positive for both urease C and cagA genes. In healthy persons,38.5 ％ of the tested samples was urease C gene posi-tive and 7.7 ％ was positive for both urease C and cagA genes. There was a significantly difference between the twogroups (P ＜0.01).The Hp-positive rate of the major periodontitis was enhanced obviously to minor peciodontitis.The Hp-positive rate of subgingival plaque was significantly higher than that of supragingival plague. Conclusion: HP participates the formation of the chronic periodontitis or it increases the pathogenic effect of other factors.关键词
幽门螺杆菌/聚合酶链反应/牙周炎Key words
helicobacter pylori/ periodontitis/ polymerase chain reaction分类
医药卫生引用本文复制引用
高静,朱声荣,刘贤,李月秀,王艳春..慢性牙周炎与口腔幽门螺杆菌的相关性研究[J].临床口腔医学杂志,2011,27(1):5-7,3.基金项目
泰安市科技局资助项目(泰科计字[2002]9号) （泰科计字[2002]9号）
