实用肝脏病杂志2011，Vol.14Issue(1)：40-41,54,3.DOI:10.3969/j.issn.1672-5069.2011.01.015
巨大原发性肝癌立体定向放射治疗计划设计
The designing of treatment plan for huge primary liver cancer treated by stereotactic radiotherapy
钟南保 1吕光明 1陈忠华 1季洪兵1
作者信息
- 1. 350025,福州市,南京军区福州总医院肿瘤放射治疗中心
- 折叠
摘要
Abstract
Objective To study the designing of treatment plan for huge primary liver cancer treated by γ-ray stereotactic radiotherapy. Methods 37 patients with huge primary liver cancer were treated with γ-ray stereotatic radiotherapy (SRT). Each planning target volume was more than 300 cm3 (vptv≥300cm3). The dose of 3200～3900cGy were delivered to PTVs with the fraction dose of 300～350cGy and 6 consecutive fractions per week. The planning targets were all surrounded by 50％～55％ isodose curve. 14～22 isocenters were needed in each treatment plan in order to cover the PTV by 50％～55％ isodose curve. The index of dose homogeneity of target was 1.60～1.72. There was no normal tissue that couldn't tolerate the irradiation involved. Results All patients were examined with image of CT or MRI. The total effective rate (CR+PR),steady disease(SD),progressive disease (PD)was 78.4％,8.1％ and 13.5％,respectively. The main gastrointestinal complications were uncomfortable upper abdomen and poor appetite. Conclusions Qualified treatment plan for huge primary liver cancer treated by γ-ray stereotactic radiotherapy could be designed,but lots of isocenters were needed in the treatment plan and the dose in the target was not homogeneous.关键词
肝癌/立体定向放射治疗/治疗计划引用本文复制引用
钟南保,吕光明,陈忠华,季洪兵..巨大原发性肝癌立体定向放射治疗计划设计[J].实用肝脏病杂志,2011,14(1):40-41,54,3.
