实用肝脏病杂志2011，Vol.14Issue(1)：18-20,3.DOI:10.3969/j.issn.1672-5069.2011.01.006
肝活检对HBV携带者的诊断意义
The histopathological manifestations in individuals with hepatitis B viral carriers
摘要
Abstract
Objective The aim of this study was to investigate the clinic significance of liver biopsy in asymptomatic chronic hepatitis B virus carriers. Methods 134 individuals with chronic hepatitis B viral carriers received the liver biopsy. Results Liver biopsies showed hepatic necrosis inflammation and fibrosis in 1.49％(2/ 134)without any change; Among 105 patients who met the HBV DNA≥ 105copies/ml(or in HBeAg negative patients was ≥ 104copies/ml),there were 80 cases whose liver inflammation ≥G2; Between 100 patients with HBeAg (+)and 34 patients with HBeAg (-),there was no significantly statistical difference in their liver inflammation and fibrosis (P=0.308);the hepatic necrosis inflammation and fibrosis between group with HBV DNA＜107copies/ml and those with HBV DNA≥l07copies/ml were statistically different(P=0.007,P=0.001). Conclusions The liver biopsy should be done in chronic hepatitis B carriers in time.关键词
慢性乙型肝炎/肝活检/病理学引用本文复制引用
凌琪华,陈建杰,陈逸云,樊丽萍,朱晖..肝活检对HBV携带者的诊断意义[J].实用肝脏病杂志,2011,14(1):18-20,3.基金项目
上海市市级医院新兴前沿技术联合攻关项目(项目批准号SHDC12006109) （项目批准号SHDC12006109）
