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洛索洛芬钠涂膜剂的制备与质量控制

王薇 刘祖雄 杨小松

医药导报2011,Vol.30Issue(1):88-90,3.
医药导报2011,Vol.30Issue(1):88-90,3.DOI:10.3870/yydb.2011.01.028

洛索洛芬钠涂膜剂的制备与质量控制

Preparation and Quality Control of Loxoprofen Sodium Plastic

王薇 1刘祖雄 1杨小松1

作者信息

  • 1. 广州军区武汉总医院药剂科,430070
  • 折叠

摘要

Abstract

Objective To study the method of preparation and quality control of loxoprofen sodium plastic. Methods Loxoprofen sodium plastic was prepared with chitosan as plastic material and high performance liquid chromatography ( HPLC) was used to determine the content of loxoprofen sodium. Results The linear range of loxoprofen sodium was 10-90μg · mL-1 , while the average recovery rate was 100. 22% , and RSD was 0. 44% (n = 9). Conclusion The preparation technology for loxoprofen sodium plastic is reasonable, and quality control is feasible, both of which are consistent with relevant regulations of plastic preparation of China pharmacopoeia(2005 edition).

关键词

洛索洛芬钠/涂膜剂/制备/色谱法,高效液相/质量控制

分类

医药卫生

引用本文复制引用

王薇,刘祖雄,杨小松..洛索洛芬钠涂膜剂的制备与质量控制[J].医药导报,2011,30(1):88-90,3.

医药导报

OA北大核心CSTPCD

1004-0781

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