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Fmr1基因敲除对小鼠生理发育和繁殖性能的影响

戴丽军 叶炳飞 黄月玲

中国比较医学杂志2011,Vol.21Issue(1):64-66,69,4.
中国比较医学杂志2011,Vol.21Issue(1):64-66,69,4.DOI:10.3969/j.issn.1671-7856.2011.01.014

Fmr1基因敲除对小鼠生理发育和繁殖性能的影响

The Infection of Fmr1 on Physiological Development and Reproductive Performance in Mice

戴丽军 1叶炳飞 1黄月玲1

作者信息

  • 1. 广州医学院实验动物中心,广州,510182
  • 折叠

摘要

Abstract

Objective To investigate the indices of physiological development and reproductive performance in FVB.KO and FVB.Method 40 seeds FVB.KO and FVB (20 male and 20 female mice, aged 10 weeks) were chose and monogamously mated.After natural delivery, the research tested the reproductive performance and indices of physiological development such as pinna detachment, body hair sprouted, incisor eruption eye opening.Result The reproductive performance and indices of physiological development but rate of male and female in FVB.KO and FVB were no difference.The rate of male and female in FVB.KO was lower.Conclusion Fmrl has no effect on behavioral development and reproductive performance in mice.But it maybe has some effects on rate of male and female in mice.

关键词

基因剔出/Fmr1/小鼠/FVB/生理发育指标/繁殖性能

分类

医药卫生

引用本文复制引用

戴丽军,叶炳飞,黄月玲..Fmr1基因敲除对小鼠生理发育和繁殖性能的影响[J].中国比较医学杂志,2011,21(1):64-66,69,4.

基金项目

广东省科技计划重点攻关项目(200560302004、2009B060300018). (200560302004、2009B060300018)

中国比较医学杂志

OACSTPCD

1671-7856

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