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丙型肝炎病毒感染与治疗药物

戚中田

临床肝胆病杂志2011,Vol.27Issue(1):15-18,27,5.
临床肝胆病杂志2011,Vol.27Issue(1):15-18,27,5.

丙型肝炎病毒感染与治疗药物

Hepatitis C virus infection and its therapeutic drugs

戚中田1

作者信息

  • 1. 第二军医大学微生物教研室,上海,200433
  • 折叠

摘要

Abstract

Hepatitis C virus (HCV) can lead to chronic hepatitis C (CHC) in ways that favor viral replication and persistent infection. The current standard treatment for hepatitis C virus infection is the combination ofpegylated IFN with ribavirin (PEG-IFN/RBV). In the recent years there has been significant advances in the understanding of viral replication and the development of anti-virus agents. This review summarizes the current knowledge of HCV cell entry, replication, escaping host innate and adaptive immune responses and current clinical trails of anti-HCV drugs.

关键词

肝炎,丙型/肝炎病毒属

Key words

hepatitis C/ hepacivirus

分类

医药卫生

引用本文复制引用

戚中田..丙型肝炎病毒感染与治疗药物[J].临床肝胆病杂志,2011,27(1):15-18,27,5.

基金项目

国家传染病重大专项课题(2008ZX10002-013) (2008ZX10002-013)

国家新药创制重大专项课题(2008ZXJ09009-002) (2008ZXJ09009-002)

上海市重点学科建设项目(B901) (B901)

临床肝胆病杂志

OACSTPCD

1001-5256

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