临床肝胆病杂志2011,Vol.27Issue(1):15-18,27,5.
丙型肝炎病毒感染与治疗药物
Hepatitis C virus infection and its therapeutic drugs
摘要
Abstract
Hepatitis C virus (HCV) can lead to chronic hepatitis C (CHC) in ways that favor viral replication and persistent infection. The current standard treatment for hepatitis C virus infection is the combination ofpegylated IFN with ribavirin (PEG-IFN/RBV). In the recent years there has been significant advances in the understanding of viral replication and the development of anti-virus agents. This review summarizes the current knowledge of HCV cell entry, replication, escaping host innate and adaptive immune responses and current clinical trails of anti-HCV drugs.关键词
肝炎,丙型/肝炎病毒属Key words
hepatitis C/ hepacivirus分类
医药卫生引用本文复制引用
戚中田..丙型肝炎病毒感染与治疗药物[J].临床肝胆病杂志,2011,27(1):15-18,27,5.基金项目
国家传染病重大专项课题(2008ZX10002-013) (2008ZX10002-013)
国家新药创制重大专项课题(2008ZXJ09009-002) (2008ZXJ09009-002)
上海市重点学科建设项目(B901) (B901)