现代妇产科进展2011,Vol.20Issue(1):39-41,3.
CCR4及CCR8在子宫内膜异位症患者在位内膜及异位灶的表达
Expression of CCR4 and CCR8 in eutopic endometrium and ectopic foci of endometriosis
摘要
Abstract
Objective:To evaluate the expression of chemokine receptors CCR4 and CCR8 in the eutopic endometrium and ectopic foci of patients with endometriosis. Methods :Immunohistochemistry was used to detect the protein expression of CCR4 and CCR8 in the eutopic endometrium and ectopic foci of endometriosis.with the endometrium of normal fertile women as control. Results:The expression of CCR4 and CCR8 in the eutopic endometrium was significantly higher than that of the normal endometrium ( P<0. 05 ) , while the expression of CCR4 and CCR8 in the ectopic foci was significantly higher than that of the eutopic endometrium ( P<0.05) . Conclusion : Our research indicates that CCR4 and CCR8 is involved in the pathogenesis and development of endometriosis.关键词
子宫内膜异位症/趋化因子受体/CCR4/CCR8分类
医药卫生引用本文复制引用
罗雪珍,史颖莉,王凌,李大金..CCR4及CCR8在子宫内膜异位症患者在位内膜及异位灶的表达[J].现代妇产科进展,2011,20(1):39-41,3.基金项目
国家重大科学研究项目(No:2006CB944007) (No:2006CB944007)
上海市医学重点学科建设项目(No:05-Ⅲ016) (No:05-Ⅲ016)
上海市重点学科建设项目(No:B117) (No:B117)
上海市医学领军人才基金项目 ()