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CCR4及CCR8在子宫内膜异位症患者在位内膜及异位灶的表达

罗雪珍 史颖莉 王凌 李大金

现代妇产科进展2011,Vol.20Issue(1):39-41,3.
现代妇产科进展2011,Vol.20Issue(1):39-41,3.

CCR4及CCR8在子宫内膜异位症患者在位内膜及异位灶的表达

Expression of CCR4 and CCR8 in eutopic endometrium and ectopic foci of endometriosis

罗雪珍 1史颖莉 1王凌 1李大金1

作者信息

  • 1. 复旦大学附属妇产科医院暨妇产科研究所,上海,200011
  • 折叠

摘要

Abstract

Objective:To evaluate the expression of chemokine receptors CCR4 and CCR8 in the eutopic endometrium and ectopic foci of patients with endometriosis. Methods :Immunohistochemistry was used to detect the protein expression of CCR4 and CCR8 in the eutopic endometrium and ectopic foci of endometriosis.with the endometrium of normal fertile women as control. Results:The expression of CCR4 and CCR8 in the eutopic endometrium was significantly higher than that of the normal endometrium ( P<0. 05 ) , while the expression of CCR4 and CCR8 in the ectopic foci was significantly higher than that of the eutopic endometrium ( P<0.05) . Conclusion : Our research indicates that CCR4 and CCR8 is involved in the pathogenesis and development of endometriosis.

关键词

子宫内膜异位症/趋化因子受体/CCR4/CCR8

分类

医药卫生

引用本文复制引用

罗雪珍,史颖莉,王凌,李大金..CCR4及CCR8在子宫内膜异位症患者在位内膜及异位灶的表达[J].现代妇产科进展,2011,20(1):39-41,3.

基金项目

国家重大科学研究项目(No:2006CB944007) (No:2006CB944007)

上海市医学重点学科建设项目(No:05-Ⅲ016) (No:05-Ⅲ016)

上海市重点学科建设项目(No:B117) (No:B117)

上海市医学领军人才基金项目 ()

现代妇产科进展

OACSCDCSTPCD

1004-7379

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