中国实用妇科与产科杂志2011，Vol.27Issue(1)：42-44,3.
宫颈高度鳞状上皮内病变治疗后高危型人乳头瘤病毒的消退规律
Clearance of high-risk human papillomavirus after treatment for high-grade squamous intraepithelial lesions
摘要
Abstract
Objective To investigate the rate of clearance of high-risk human papillomavirus (HPV) infection after loop electrosurgical excision procedure(LEEP) for high-grade squamous intraepithelial lesions, and to study the relation between high-risk HPV persistent infection and residual/recurrent disease after LEEP.Methods A retrospective study was conducted on 502 women who underwent LEEP for high-grade squamous intraepithelial lesions between January 2003 and December 2007 in the Guangdong General Hospital.Results Among those who were high-risk HPV infected before LEEP, the clearance rate of high-risk HPV was 83.63％, 94.39％, 97.31％ ,and 98.88％ after treatment 6 months, 12 months, 18 months and 24 months, respectively.Of women with high-risk HPV persistent infection after LEEP, 26.85％ developed residual/recurrent disease.Conclusion LEEP is an important treatment for high-grade squamous intraepithelial lesions,and it is a highly effective method of eradicating HPV.HPV-DNA testing is a useful means for monitoring the efficacy of treatments during follow-up.We suggest the initial testing should perform at 6 months for the follow-up.关键词
宫颈高度鳞状上皮内病变/人乳头瘤病毒分类
医药卫生引用本文复制引用
陈观娣,钱德英,岑坚敏,舒焰红,欧阳云雁,郑有为..宫颈高度鳞状上皮内病变治疗后高危型人乳头瘤病毒的消退规律[J].中国实用妇科与产科杂志,2011,27(1):42-44,3.基金项目
广东省科技计划项目基金(2002B30404) （2002B30404）
