肿瘤防治研究2011，Vol.38Issue(1)：77-79,3.DOI:10.3971/j.issn.1000-8578.2011.01.022
胶质瘤的CT灌注成像与微血管密度的相关性
Correlations between CT Perfusion Imaging and Microvessel Density in Gliomas
摘要
Abstract
Objective To discuss the correlations between relative cerebral blood volume (rCBV) value of CT perfusion imaging and microvessel density(MVD), and to explore the value of rCBV for preoperative grading of gliomas. Methods Thirty cases of glioma patients (11 low grade and 19 high grade astrocytomas) underwent conventional CT and CT perfusion imaging examination before operation.The absolute and relative value of CBV were measured in the parenchyma part of glioma and were processed statistically. The mean MVD of the lesions were measured immunohistochemically in all the histologie specimens. The relationship between rCBV and MVD were analyzed. Results The rCBV value had significantly positive( r = 0. 562, P＜0. 05) correlation with MVD. The mean values of rCBV in low and high grade gliomas were (2. 31 ± 0. 28) and (4. 69 ± 1.65) respectively. The value of rCBV between the two groups showed significant differences. Conclusion The value of rCBV is in good agreement with MVD, and is valuable for preoperative grading of gliomas in clinical procedures.关键词
体层摄影术/X线计算机/灌注成像/胶质瘤/微血管密度分类
医药卫生引用本文复制引用
黄劲柏,任伯绪,雷红卫,蔡新宇,熊浩,陈昌毅..胶质瘤的CT灌注成像与微血管密度的相关性[J].肿瘤防治研究,2011,38(1):77-79,3.基金项目
湖北省教育厅科研基金资助项目(Q20081203) （Q20081203）
