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呼吸科重症监护病房非铜绿假单胞菌感染特征和耐药性分析

王悦 张鲁涛 史利克 刘燕

中国全科医学2011,Vol.14Issue(6):645-647,3.
中国全科医学2011,Vol.14Issue(6):645-647,3.

呼吸科重症监护病房非铜绿假单胞菌感染特征和耐药性分析

Infection Feature and Drug Resistance of No-Pseudomonas Aeruginosa in Respiratory ICU

王悦 1张鲁涛 2史利克 1刘燕1

作者信息

  • 1. 050000,河北省石家庄市,河北医科大学第二医院感染管理科
  • 2. 050000,河北省石家庄市,河北医科大学第二医院呼吸内科
  • 折叠

摘要

Abstract

Objective To determine the spectrum and drug resistance of no - pseudomonas aeruginosa in respiratory intensive care unit ( RICU ), and to provide basis for proper use of antibiotics and prevent and control infection in the hospital. Methods The data on drug resistance of no - Pseudomonas aeruginosa isolated from the RICU in our hospital from 2004 to 2008 was retrospectively analyzed. Results Totally 108 strains of no-Pseudomonas aeruginosa were isolated, of which 66 were Stenotrophomonas maltophilia strains ( 66. 11% ), 29 were Burkholderia cepacia strains ( 26. 85% ). Sputum was the main source of no-Pseudomonas aeruginosa ( 96. 30% , 104 /108 ). The results of drug susceptibility showed that the resistance rate of no - Pseudomonas aeruginosa to most drugs were high; the resistance rates of Stenotrophomonas maltophilia to minocycline, gatifloxacin and levofloxacin were low, being 3. 45% , 29. 63% and 33. 33% respectively; the resistance rates of Burkholderia cepacia to meropenem and piperacillin/tazobactam were lowest, being 24. 00% and 28. 57% respectively. Conclusion The most common strains of no-Pseudomonas aeruginosa are Stenotrophomonas maltophilia and Burkholderia cepacia, and the most common site of infection is lower respiratory tract. The no - Pseudomonas aeruginosa shows high and multiple drug resistance, so clinical treatment of no-Pseudomonas aeruginosa infection should be based on the results of the drug susceptibility tests.

关键词

呼吸科重症监护病房/非铜绿假单胞菌/嗜麦芽窄食单胞菌/洋葱伯克霍尔德菌/耐药性

分类

医药卫生

引用本文复制引用

王悦,张鲁涛,史利克,刘燕..呼吸科重症监护病房非铜绿假单胞菌感染特征和耐药性分析[J].中国全科医学,2011,14(6):645-647,3.

中国全科医学

OA北大核心CSTPCD

1007-9572

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