国际医药卫生导报2011，Vol.17Issue(1)：1-4,4.DOI:10.3760/cma.j.issn.1007-1245.2011.01.001
30日龄Fmr1基因敲除小鼠的自主活动观察
Behavioural comparision on Fmr1 knockout mice at 30 days age in spontaneous activity test
摘要
Abstract
Objective To compare the behavioural differences at 30 days age in spontaneous activity test. Methods Fmr1 knockout mice were identified using the PCR technica. and spontaneous activity test was used in the study .The data was analyzed with Multifactor Variance Analysis. Results Activities in their own experiments, as compared with WT mice, KO mice in the experiment of self-activity increase in the number of activities and reduction in the number of standing, with statistical significance ( P＜0.05 ), but there were no significant differences on manure behaviour between two groups. Conclusion Fmr1 knockout animals exhibited higher locomotor activity in the spontaneous activity test at 30 days age.关键词
自主活动/Fmr1基因敲除小鼠Key words
Spontaneous activity test/Fmr1 knockout mice/Behaviour引用本文复制引用
张伟雯,黄越玲,刘国彬,沈岩松,孙卫文,李敏雄,戴丽军,陈盛强..30日龄Fmr1基因敲除小鼠的自主活动观察[J].国际医药卫生导报,2011,17(1):1-4,4.基金项目
广州市医药卫生科技项目(2009-YB-167) （2009-YB-167）
广东省自然科学基金项目(815101700100005) （815101700100005）
广东省科技计划项目(2005B60302004、2008B030301371、2009B030801368) （2005B60302004、2008B030301371、2009B030801368）
广州市中医药中西医结合科研立项项目(2008A52) （2008A52）
