摘要
Abstract
Objective To study the effectiveness and feasibility of the propofol target-controlled infusion (TCI) in the extubating period of general anesthesia to prevent cardiovascular response.Methods 60 patients who were in the ASA Ⅰ～Ⅱclass and seleetived abdominal surgery were randomly divided into the Propefol group (A) and the control group (B).Extubating in the same eircumstanees and conditions, A group were given with propofol TCI, Marsh model, keep the target plasma concentration as 1μ g/ml. and the drug withdrawal was 5rain after extubating; B group was not given the Propofol TCI,they were extubated after the sputum aspiration.The breathing rate, heart rate, MAP and SpO2 were continuous monitoring in the intraoperative, before using the TCI,during the extubating, 5min and 10min after extubatiug.And the time to recover the breathing, the time for extubating, the conscious level, the adverse effect and so on were also monitoring.Results during the extuhating, 5rain and 10min after the extubating, the breathing rate, the heart rate, MAP were declined slightly than that before using the TCI.And there was significantly lower in the A group than the B group (P < 0.05), B group, The value of SpO2 was significantly lower than the basis of value during extubating and the sputum aspiration(P < 0.05).Conclusions Propofol target-controlled infusion using in the extubating period of general anesthesia, the stress reaction of the body was small,and the vital signs were stable in the process of extubating.关键词
全麻拔管期/丙泊酚/靶控输注Key words
Extubating period of general anesthesia/Propofoi/Target controlled infusion
