首页|期刊导航|东华大学学报（英文版）|Silk Fibroin-modified Poly (butadiene) urethane Films and Their Effects on Fibroblast Viability
东华大学学报（英文版）2008，Vol.25Issue(6)：680-685,6.
Silk Fibroin-modified Poly (butadiene) urethane Films and Their Effects on Fibroblast Viability
Silk Fibroin-modified Poly (butadiene) urethane Films and Their Effects on Fibroblast Viability
摘要
Abstract
Surface-modified poly ( butadiene) urethane (PBTU) films with silk fibroin (SF) were prepared by simple chemical method under the normal temperature.The physical properties and biological behaviour of the SF-modified PBTU film were evaluated.The results showed that the SF-modified PBTU films kept the tenacity and pliability very well, and could overcome rigid and brittle weaks of silk fibroin films.The morphology of SF in the PBTU film was dendritic aggregations, and the water-contact angle measurement indicated that the surface hydrophilicity of modified films was apparently enhanced.The biocompatibility of PBTU films was improved due to the change of surface components.The degree of platelet adhesion and the cell viability of rat embryo dermal fibrobiasts seeded on PBTU films, SF films, and SF-modified PBTU films were measured by counting platelets before and after they contacted the films and Mil assay, respectively.The results indicated that platelet adhesion resistance and cell viability on the modified film were greatly superior to those on the PBTU film and the compound interface had good stability in the air.关键词
poly (butadiene) urethane/silk fibroin/modification/fibroblast/platelet adhesionKey words
poly (butadiene) urethane/silk fibroin/modification/fibroblast/platelet adhesion分类
化学化工引用本文复制引用
SUN Dong-hao,WU Zheng-yu,LI Ming-zhong,BAI Lun,SHENG Wei-hua..Silk Fibroin-modified Poly (butadiene) urethane Films and Their Effects on Fibroblast Viability[J].东华大学学报（英文版）,2008,25(6):680-685,6.基金项目
Foundation item: Major State Basic Research Development Program of China (No.2005CB623906) （No.2005CB623906）
