中国普通外科杂志2011,Vol.20Issue(1):32-35,4.
原发性肝癌切除术后高胆红素血症临床分析
Clinical investigation on postoperative high serum bilirubin in patients with primary liver cancer after resection
黄涛 1周进学 1杨楠木 1宫东伟1
作者信息
- 1. 河南省肿瘤医院肝胆胰外科,河南郑州450008
- 折叠
摘要
Abstract
Objective To investigate the features of postoperative serum bilirubin changes and the clinical factors associated with high serum bilirubin level in patients with primary liver cancer after resection. Methods The clinical data of 97 patients with primary liver cancer who underwent hepatectomy were analysed retrospectively. The cases were divided into two groups: high serum bilirubin group and normal bilirubin group, respectively, according to serum bilirubin level during two weeks after operation. The features of postoperative serum bilirubin changes and the causitive factors of postoperative high serum bilirubin were analyzed. Results The postoperative serum bilirubin reached the peak value [ (21. 5 ± 9.2 )μmol/L ] on d4, and then decreased to normal on d 14 in normal bilirubin group. But in high serum bilirubin group the postoperative serum bilirubin reached the peak value [ (49.2 ± 25.4 )μmol/L] on the d7, and was still twice more than the normal value [ ( 36.1 ± 17.6 ) μmol/L ] on d 14. Preoperative serum bilirubin, Child's grade, types of hepatic vascular occlusion, blood loss, blood transfusion, and postoperative hyponatremia were related with postoperative high serum bilirubin. Preoperative serum bilirubin was an independent factor in predicting postoperative high serum biliruhin ( OR = 5. 406, x2 = 11.319, P = 0.001 ). Conclusions It is very important to monitor the posthepatectomy serum bilirubin value dynamically. Preventon and treatment of the causes of perioperative high serum bilirubin may help to decrease the complications of hepatectomy.关键词
肝肿瘤/外科学/肝切除术/血清胆红素/手术后并发症/预防与控制分类
医药卫生引用本文复制引用
黄涛,周进学,杨楠木,宫东伟..原发性肝癌切除术后高胆红素血症临床分析[J].中国普通外科杂志,2011,20(1):32-35,4.