中华医学杂志（英文版）2011，Vol.124Issue(3)：445-456,12.DOI:10.3760/cma.j.issn.0366-6999.2011.03.023
Current status and progress in gastric cancer with liver metastasis
Current status and progress in gastric cancer with liver metastasis
摘要
Abstract
Objective This review discusses the current status and progress in studies on gastric cancer with liver metastasis (GCLM), involving the routes, subtypes, and prognosis of GCLM; the genes and molecules associated with metastasis;the feasibility and value of each imaging modality; and current treatment options.Data sources The data used in this review were mainly from Medline and PubMed published in English from 2005 to August 2010. The search terms were "gastric cancer" and "liver metastasis".Study selection Articles regarding the characteristics, diagnostic modalities, and vadous therapeutic options of GCLM were selected.Results The prognosis of GCLM is influenced by the clinicopathological characteristics of primary tumors, as well as the presence of liver metastases. Improved understanding of related genes and molecules will lead to the development of methods of early detection and targeted therapies. For the diagnosis of GCLM, each imaging modality has its relative benefits. There remains no consensus regarding therapeutic options.Conclusions Early detection and characterization of liver metastases is crucial for the prognosis of gastric cancer patients. Multidisciplinary team discussions are required to design optimal treatment strategies, which should be based on the clinicopathological characteristics of each patient.关键词
gastric cancer/liver metastasis/diagnostic imaging/therapeuticsKey words
gastric cancer/liver metastasis/diagnostic imaging/therapeutics引用本文复制引用
LIU Jing,CHEN Lin..Current status and progress in gastric cancer with liver metastasis[J].中华医学杂志（英文版）,2011,124(3):445-456,12.基金项目
This study was supported by the National Basic Science and Development Program (863 program No. 2006AA02A402) and National Natural Science Foundation of China (No. 30872468). （863 program No. 2006AA02A402）
