首页|期刊导航|中华医学杂志（英文版）|Incidence and prevention of venous thromboembolism in acutely ill hospitalized elderly Chinese
中华医学杂志（英文版）2011，Vol.124Issue(3)：335-340,6.DOI:10.3760/cma.j.issn.0366-6999.2011.03.003
Incidence and prevention of venous thromboembolism in acutely ill hospitalized elderly Chinese
Incidence and prevention of venous thromboembolism in acutely ill hospitalized elderly Chinese
摘要
Abstract
Background As the third most frequent cardiovascular disease, venous thromboembolism (VTE) remains a major cause of morbidity and mortality in hospitalized patients. The aim of this study was to determine the incidence of VTE and steps for its prevention in acutely ill hospitalized elderly Chinese patients.Methods A prospective multi-center study was conducted from June 2006 to November 2007. A total of 607 patientsfrom 40 research centers in China were enrolled. Data of the patients' baseline characteristics, VTE events and prophylaxis/therapy methods were collected.Results Fifty-nine patients (9.7%) had an objectively confirmed VTE during the 90-day follow-up, of which, 59.3%occurred during the first week and 75% within 14 days. Forty-one patients died (6.6%) during the follow-up, 36.6% died within three weeks. We also found that medical disorders including respiratory failure (16.4%), acute brain infarction (15.6%), acute infectious diseases (14.3%), acute coronary artery syndrome (8.7%) and heart failure (7.6%) play a role in provoking VTE. Only 13.0% of the elderly patients with high risk of VTE used low dose unfractionated heparin, 7.1% used low molecular weight heparin, 5.4% used warfarin,0.3% used graduated compression stockings and none of them used intermittent pneumatic compression.Conclusions Our study showed similar results between our study and western countries in the VTE incidence by day 90 in elderly hospitalized patients with acute medical illness. Great caution must be applied in the care of acutely ill elderly hospitalized patients to deal with the complications of VTE. Application of safe and effective prophylaxes against embolism remains a critical challenge.关键词
venous thromboembolism/deep venous thrombosis/pulmonary embolismKey words
venous thromboembolism/deep venous thrombosis/pulmonary embolism引用本文复制引用
LI Xiao-ying,FAN Jin,CHENG You-qin,WANG Yan,YAO Chen,ZHONG Nan-shan..Incidence and prevention of venous thromboembolism in acutely ill hospitalized elderly Chinese[J].中华医学杂志（英文版）,2011,124(3):335-340,6.基金项目
This work was supported by grants from Pfizer Pharmaceuticals Ltd. (China) and from GlaxoSmithKline Investment Co Ltd.(China). （China）
