高等学校化学学报2011，Vol.32Issue(1)：74-78,5.
含七氟异丙基的氯虫酰胺类似物的设计合成及生物活性
Design, Synthesis and Biological Activities of Novel Analogues of Chlorantraniliprole Containing Heptafiuoroisopropyl Group
摘要
Abstract
In order to find novel insecticides targeting the ryanodine receptor with high activity, a series of novel analogues of chlorantraniliprole containing heptafluoroisopropyl group, developed from the structures of chlorantranili-prole and fiubendiamide, was designed and synthesized according to the substructure link principle. Their structures were characterized by 1H NMR and HRMS. Their evaluated insecticidal activities show that the introduction of the heptafluoroisopropyl group decreases the activitiy sharply. At the concentration of 100 mg/L, compounds 4b and 6a show insecticidal activities with 100％ and 80％, respectively. In addition,these analogues exhibite certain fungicidal activities.关键词
氯虫酰胺/氟虫酰胺/七氟异丙基/杀虫活性/杀菌活性Key words
Chlorantraniliprole/ Flubendiamide/ Heptafluoroisopropyl group/ Insecticidal activity/ Fungicidal activity分类
化学化工引用本文复制引用
冯启,刘智力,王明忠,熊丽霞,于淑晶,李正名..含七氟异丙基的氯虫酰胺类似物的设计合成及生物活性[J].高等学校化学学报,2011,32(1):74-78,5.基金项目
国家"九七三"计划项目(批准号:2010CB126106)和国家自然科学基金(批准号:20872069)资助. （批准号:2010CB126106）
