感染、炎症、修复2011，Vol.12Issue(1)：43-45,3.
3项肿瘤标志物联合检测在肺癌诊断中的价值
The evaluation of three tumor markers in diagnosis of lung cancer
刘刚 1顾春瑜 1侯晓霞 1赵乔妹 1于勇1
作者信息
- 1. 解放军总医院第一附属医院检验科,北京,100048
- 折叠
摘要
Abstract
To study the clinical significance of combination detection of carcino-embryonic antigen (CEA), CYFRA21-1 and neuron-specific enolase (NSE) in patients with lung cancer. Methods: One hundred and thirteen cases of lung tumor patients and 60 patients with benign lung diseases were enrolled. Their serum levels of CEA, CYFRA21-1 and NSE were detected by electro-chemi-luminescence assay. Results: The levels of CEA,CYFRA21-1 and NSE in lung cancer group were significantly higher than those of control group (P＜0. 01). The sensitivity and specificity of measurement of three tumor markers in combination (79. 6％) were significantly higher than that of combination of two tumor markers(67. 3％ ,70. 8％ and 65. 5％ in different combinations)and single tumor marker(46. 9％ ,46. 9％ and 45. 1％). Conclusion: The combined measurement of serum CEA,CYFRA21-1 and NSE significantly increased the sensitivity for diagnosis of lung cancer, and therefore it provides useful information for early diagnosis of patients with lung cancer.关键词
肺癌/癌胚抗原/细胞角蛋白19片段/神经元特异性烯醇化酶Key words
Lung cancer；Carcino-embryonic antigen；CYFRA21-1；Neuron-specific enolase引用本文复制引用
刘刚,顾春瑜,侯晓霞,赵乔妹,于勇..3项肿瘤标志物联合检测在肺癌诊断中的价值[J].感染、炎症、修复,2011,12(1):43-45,3.
