感染、炎症、修复2011,Vol.12Issue(1):41-42,封3,3.
抽动秽语综合征PET脑代谢显像的研究
Study of 18 F-fluorodeoxyglucose positron emission tomography images in the Tourette syndrome
唐玲 1欧阳巧洪 2王瑞霞 1董雪雅1
作者信息
- 1. 首都医科大学附属复兴医院核医学科,北京,100038
- 2. 解放军总医院第一附属医院核医学科,北京,100048
- 折叠
摘要
Abstract
Objective: To observe the characteristics of cerebral blood flow by positive emission tomography (PET) in the patients with Tourette Syndrome (TS) and to localize the abnormal region of cerebral glucose metabolism. Methods: The brains of 65 patients with TS were scanned with PET after administration of 18 F-fluorodeoxyglucose (18F-FDG). The patient’s images which were obtained through computer processing were analyzed in detail. Results: There were 61 abnormal PET images in the 65 patients, the positive rate was 93. 8%. Lowered distribution of radiation was found in abnormal region in form of hypometabolism. The predominant abnormal regions were frontal lobe [the rate of positive focus on the right side was 30 cases (49%) and on the left side 9 cases (14. 7%) and parietal lobe [the positive focus on the left side was 45.9% (28 cases) and on the right side was 14. 7%(9 cases) ]. The positive rate of multi-focus was 62. 3% (38 cases), and that of the single-focus was 39.3% (24 cases). Conclusion: Cerebral dysfunction was found in most of the patients with TS. 18F-FDG PET is very useful in the diagnosis of TS, and decreased distribution of radio-active isotope in the diseased parts of the brain.关键词
抽动秽语综合征/PET/18氟-脱氧葡萄糖Key words
Tourette syndrome/ Positron emission tomography/ 18 F-fluorodeoxyglucose引用本文复制引用
唐玲,欧阳巧洪,王瑞霞,董雪雅..抽动秽语综合征PET脑代谢显像的研究[J].感染、炎症、修复,2011,12(1):41-42,封3,3.