摘要
Abstract
MicroRNA (miRNA), which are small noncoding RNAs of 21-2.5 nucleotides in length existed in animals and plants, is characteristic of high conservation and endogenous. They regulate the expression of genes and take part in cell differentiation, proliferation, apoptosis, and tumorigenesis, DNA hypomethylation, chromphil change and so on. The article elaborares miRNA whose biosynthesis, mechanism of action and improvements of some studies in gynecological neoplasms.关键词
微RNAs/卵巢肿瘤/宫颈肿瘤/子宫内膜肿瘤/基因表达调控/DNA甲基化Key words
MicroRNAs/ Ovarian neoplasms/ Uterine cervical neoplasms/ Endometrial neoplasms/ Gene expression regulation/ DNA methylation