国际妇产科学杂志2011，Vol.38Issue(1)：60-63,4.
卵巢肿瘤干细胞耐药机制研究进展
Research Progress in Determing the Relationship Between Ovarian Cancer Stem Cells and Chemoresistance
吴开元1
作者信息
- 1. 450052,郑州大学第一附属医院妇产科
- 折叠
摘要
Abstract
A major problem in the treatment of ovarian cancer is the high percentage of recurrence and chemoresistance. Cancer stem cells (CSCs) can proliferate indefinitely, be proved enhancing chemoresistance and indicate a close relationship with chemoresistance. CSCs with definite cell surface maker can be separated from chemoresistant ovarian cancer cells, they can provide a reservoir of cells that can self-renew, maintain the tumor which make up the bulk of the tumor and may be the primary source of recurrence and chemoresistance. According to the special cell-surface marker and making chemotherapeutics selectively binding with ovarian cancer stem cells, can eliminate cancer recurrence and chemoresistance thoroughly and provide more effective chemotherapy shedules.关键词
卵巢肿瘤/肿瘤干细胞/抗药性,肿瘤/生物学标记/免疫/多药耐药相关蛋白质类Key words
Ovarian neoplasms/ Neoplastic stem cells/ Drug resistance, neoplasm/ Biological markers/Immunity/ Multidrug resistance-associated proteins引用本文复制引用
吴开元..卵巢肿瘤干细胞耐药机制研究进展[J].国际妇产科学杂志,2011,38(1):60-63,4.
