实用医学杂志2011，Vol.27Issue(1)：61-64,4.DOI:10.3969/j.issn.1006-5725.2011.01.026
晚发型多发性硬化临床特点分析
Clinical analysis of late-onset multiple sclerosis
摘要
Abstract
Objective To summarize the clinical features of late-onset multiple sclerosis (LOMS). Methods Compared with 215 patients with adult-onset multiple sclerosis in the same period, 33 patients with late-onset multiple sclerosis were analyzed retrospectively from general information, clinical features and ancillary examinations. Results The age of first-episode was from 50 to 71 years, with an average age of 53.82 years, the ratio of male to female was 1:1.54; LOMS were found to be subacute or chronic at onset, accounted for 72.7％; Among 33 LOMS cases, 33.3％ of them was relapsing-remitting type, and 21.2％ was primary progressive type in clinical classification; The initial symptoms were commonly limb numbness and limb weakness, seizure presented single symptom, movement disorders and paraesthesia were common in clinical manifestations; Prognosis may be related to clinical types. Conclusion The clinical features of LOMS are similar to adult-onset multiple sclerosis, but the emphasis on movement disorders and spinal cord injury are more common; MRI and evoked potentials are helpful to its early diagnosis.关键词
多发性硬化/晚发型/临床特点引用本文复制引用
张先龙,唐玉兰,肖凯文..晚发型多发性硬化临床特点分析[J].实用医学杂志,2011,27(1):61-64,4.基金项目
广西自然科学基金资助项目(编号:桂科回0991009) （编号:桂科回0991009）
广西卫生厅自筹经费科研课题资助项目(编号:Z2009097) （编号:Z2009097）
