畜牧与兽医2011，Vol.43Issue(1)：23-26,4.
迟缓爱德华菌人工感染斑马鱼的致病性及组织病理学变化
The pathogenicity and histopathological changes of artificially infected zebrafish with Edwardsiella tarda
摘要
Abstract
Clinical manifestations and pathological changes were observed after the zehrafish were artificially infected with Edwardsiella tarda strain CD ( E. t-CD) . The results showed that the median lethal dose ( LD50) for zebrafish was 2. 69×l02 cfu/fish, and the infected fish showed bleeding, ulcers , ascites, sepsis and other symptoms. Histopathological observation showed that swelling degeneration, atrophy, necrosis and abscission in the liver cells; scattered hyperplastic nodules, congestion, edema and absence of lymphocyte in the spleen cells. The results indicated that the zebrafish could be used as the animal models for studying the pathogenicity of E. tarda.关键词
迟缓爱德华菌/斑马鱼/致病性/病理学分类
农业科技引用本文复制引用
彭国瑞,王成龙,王雪鹏,陆承平..迟缓爱德华菌人工感染斑马鱼的致病性及组织病理学变化[J].畜牧与兽医,2011,43(1):23-26,4.基金项目
国家大学生创新性实验计划项目(GJ0710) （GJ0710）
浙江省近岸水域生物资源开发与保护重点实验室开放课题基金(2010F30003) （2010F30003）
山东农业大学青年科技创新基金. （）
