重庆医学2011，Vol.40Issue(3)：221-223,封2,4.DOI:10.3969/j.issn.1671-8348.2011.03.005
CD83、Ki-67在大肠癌中的表达及预后意义
Expressions of CD83,Ki-67 in colorectal carcinoma and its prognostic significance
摘要
Abstract
Objective To investigate the CD83 ,Ki-67 in colorectal carcinoma and its prognostic significance. Methods ≥ 5-year survival group and death group ＜ 3 years, 30 cases of colorectal cancer patients, used immunohistochemical staining and flow cytometry to detect colorectal cancer CD83, Ki-67 expression analysis with clinical pathology of colorectal cancer characteristics and prognosis. Results Immunohistochernistry showed that CD83 expression increased with Dukes staging decreasad,≥ 5-year survival group expressed higher than the ＜3-year death group(P＜0. 05) ; Ki67 expression increased with Dukes staging increased,≥ 5 year survival group expressed less than the ＜ 3-year death group(P＜0. 05). Flow cytometry showed that in different points during the Dukes colorectal, CD83 expression in colorectal cancer tissues in A phase and B phase was significantly higher than C phase and D phase colorectal cancer organizations(P＜0. 05) ; Ki-67 A phase and B phase colorectal cancer tissues was significantly lower than Phase C phase and D phase in colorectal cancer(P＜0. 05). Groups of≥ 5 year survival than Ki-67 expression in ＜ 3-years of death group(P＜0. 05). Conclusion Colorectal CD83 , Ki-67 expression and prognosis related to detection of colorectal cancer prognosis can be used as a reference indicator.关键词
结直肠肿瘤/预后/Ki-67抗原/CD83引用本文复制引用
黄良勤,杨伟明,刘宙,赵洪远,王超宇,邬江华,梁爽..CD83、Ki-67在大肠癌中的表达及预后意义[J].重庆医学,2011,40(3):221-223,封2,4.基金项目
贵州省优秀科技教育人才省长专项资金资助项目[(2007)79] （2007）
贵州省卫生厅科学技术基金资助项目[D-280] （）
遵义医学院附属医院硕士启动基金资助项目[(2008)33]. （2008）
