重庆医学2011,Vol.40Issue(3):246-247,2.DOI:10.3969/j.issn.1671-8348.2011.03.015
系统性红斑狼疮患者抗中性粒细胞胞浆抗体的临床相关性及其意义
Clinical correlation and significance of ANCA in patients with systemic lupus erythematosus
叶荻庆 1向瑜 1张莉萍1
作者信息
- 1. 重庆医科大学附属第一医院检验科,400016
- 折叠
摘要
Abstract
Objective To analyze the lab detection of clinical significance on ANCA in patients with SLE. Methods Indirect immunofluorescence was used to detect ANA,dsDNA,ANCA. Positive rate and immunofluorescence model of serum ANCA of 70 patients with SLE were analyzed retrospectively. Results 19 peripheral-ANCA(pANCA)were positive. dsDNA was positive,complement C3 , C4 decreased, blood sedimentation increased,and kidney damage in ANCA positive group was significantly different compared ANCA negative group(P<0. 05). Conclusion The positive ANCA in patients with SLF is correlated with the development of the disease and kidney damage.关键词
抗体,抗中性白细胞胞质/红斑狼疮,系统性/荧光抗体技术引用本文复制引用
叶荻庆,向瑜,张莉萍..系统性红斑狼疮患者抗中性粒细胞胞浆抗体的临床相关性及其意义[J].重庆医学,2011,40(3):246-247,2.