华西口腔医学杂志2011，Vol.29Issue(1)：96-99,4.DOI:10.3969/j.issn.1000-1182.2011.01.023
偏侧咀嚼致咀嚼肌功能紊乱发病机制的研究
Research about the mechanism in masticatory muscle dysfunctional induced by hemimastication
摘要
Abstract
Objective To study the mechanism in masticatory muscle dysfunctional induced by hemimastication.Methods Ca2+ contents were measured with atomic absorption spectrometry; calcinuerin were measured with colorimetric method; muscle fiber types were measured with adenosine-triphosphate (ATPase) staining. Results 1)Compared with the controls, Ca2+ contents in experimental group had the higher level except 8 weeks (P＜0.05). 2)The ratio of slow fiber in experimental group increased, higher than the match groups (P＜0.05). 3)With Ca2+ contents rise, the activities of calcinuerin present a bell-like shape. 4)The ratio of slow-type fiber was positively correlated to the activities of calcinuerin (r=0.876, P＜0.05). Conclusion The signal way of muscle fiber growth and fiber transformation were activated by high concentration of calcium, then, muscle fiber transfered from fast to slow type. It may play an important role in the mechanism that hemimastication result in masticatory muscles dysfunction.关键词
偏侧咀嚼/钙调神经磷酸酶/肌纤维类型/肌功能紊乱Key words
bemimastication/ calcinuerin/ muscle fiber type/ masticatory muscles dysfunction分类
医药卫生引用本文复制引用
王子娴,徐龙博,祁冬,林雪芬,应王贵,孙圣军,陈彬,汲平..偏侧咀嚼致咀嚼肌功能紊乱发病机制的研究[J].华西口腔医学杂志,2011,29(1):96-99,4.基金项目
山东省自然科学基金资助项目(Y2006c216) （Y2006c216）
