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龙葵多糖对H22荷瘤小鼠红细胞膜功能的影响

袁洪亮

哈尔滨商业大学学报(自然科学版)2011,Vol.27Issue(1):7-11,5.
哈尔滨商业大学学报(自然科学版)2011,Vol.27Issue(1):7-11,5.

龙葵多糖对H22荷瘤小鼠红细胞膜功能的影响

Effects of solanum nigrum polysaccharide on functioning of erythrocyte membrane of H22 tumor - bearing mice

袁洪亮1

作者信息

  • 1. 哈尔滨商业大学,生命科学与环境科学研究中心,哈尔滨,150076;国家教育部,抗肿瘤天然药物工程研究中心,哈尔滨,150076
  • 折叠

摘要

Abstract

To study the effect of solanum nigrum polysaccharide on the functioning of red cell membrane in H22 tumor- bearing mice. The membrane fluidity of red cells was measured by fluorescence spectrophotometer with DPH fluorescence probe as a marker; the amount of sialic acid and SOD on the surface of red cell membrane and the sealability of erythrocyte membrane were measured using colorimetric analysis assay. Solanum nigrum polysaccharide reduced the membrane microviscosity, at the same time, enhanced the membrane fluidity of red cells in H22 tumor - bearing mice, while increasing the amount of sialic acid and SOD in the membrane of red cells in these mice and enhancing the ability of the membrane of their red cells to reseal. The anti - tumor effect of solanum nigrum polysaccharide on H22 tumor bearing mice may be due to its ability to improve and restore the functions of the erythrocyte membrane.

关键词

龙葵多糖/H22荷瘤小鼠/红细胞膜

Key words

solanum nigrum polysaccharide/ H22 tumor- bearing mice/ erythrocyte membrane

分类

医药卫生

引用本文复制引用

袁洪亮..龙葵多糖对H22荷瘤小鼠红细胞膜功能的影响[J].哈尔滨商业大学学报(自然科学版),2011,27(1):7-11,5.

基金项目

教育部博士点基金项目(20092332110001) (20092332110001)

黑龙江省自然科学基金(D200931) (D200931)

国家教育部重点科研项目(210059). (210059)

哈尔滨商业大学学报(自然科学版)

OACSTPCD

1672-0946

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