基础医学与临床2011，Vol.31Issue(1)：6-8,3.
复发性外阴阴道念珠菌病患者及性伴侣带菌情况分析
Analysis of yeast species from patients with recurrent vulvovaginal candidiasis and patients' sexual partners
摘要
Abstract
Objective To explore the factors related to the recurrence of vulvovaginal candidiasis(RVVC). Methods Samples were collected from the discharge of vagina, rectum, oral cavity of 55 patients and the discharge of balanus in their 45 sexual partners. Using SSCP analysis of internal transcribed spacer (ITS) region and sequence analysis of the 26S rDNA D1/D2 domain to identify the species of C. albicans of the samples. Genotypes of C. albicans strains were determined with use of SSCP combined to GeneScan analysis of microsatellite CAI of C. albicans. Results The positive rate of vagina, oral and rectal Candida species colonization in the 55 women and 45 men was 100. 0％ (55/55) ,61.8％ (34/55) ,1.8％ (1/55) and 60. 0％ (27/45) ,respectively. And the percentage of Candida strains among the vagina, rectum and balanus were concurrent. In the same person, the coincidence of Candida albicans genotype between the discharge from vagina and rectum were 86. 2％. 54. 5％ of the Candida albicans genotype of the discharge from the vagina of RVVC patients were same as the discharge from the balanus of her sexual partner. Conclusion The state of having Candida on the rectum or the balanus of sexual partner is one of the potential risk factors of RVVC.关键词
复发性外阴阴道念珠菌病/基因型/单链构象多态性/基因扫描Key words
vulvovaginal candidiasis/ genotype/ SSCP/ genescan分类
医药卫生引用本文复制引用
宗利丽,王彩丽,曾俊,王玉凤,赵欣,毛婷..复发性外阴阴道念珠菌病患者及性伴侣带菌情况分析[J].基础医学与临床,2011,31(1):6-8,3.基金项目
国家高技术研究发展计划(863计划)(102-09-03-06) （863计划）
