神经损伤与功能重建2011，Vol.6Issue(2)：118-122,5.DOI:10.3870/sjsscj.2011.02.010
心理干预辅助药物治疗帕金森病抑郁与认知障碍
Effects of Psychotherapy on Depression and Cognitive Impairment in Patients with Parkinson's Disease
梅俊华 1邵卫 1周景芬 1陈国华 1笱玉兰 1潘晓峰1
作者信息
- 1. 武汉市第一医院神经内科,武汉,430022
- 折叠
摘要
Abstract
Objective: To explore the effects of psychotherapy on depression and cognitive impairment in patients with Parkinson's disease (PD). Methods: Seventy PD patients were randomly divided into psychotherapy group (n=35) and medication group (n=35). The depressive symptoms and cognitive impairment were assessed at days 0, 7 and 60, using the MMSE, MoCA, SDS, and HAMD scales. Results: Depressive symptoms and cognitive impairment were found in patients with PD. No significant difference of scores was observed at day 7 after psychotherapy. At day 60, HAMD and SDS scores were significantly lower than those at days 0 and 7 in psychotherapy group (P＜0.05). According to MMSE test, the total score, factor orientation score, calculation, and speech were significantly higher at day 60 than those in psychotherapy group at days 0 and 7 (P＜0.05). MoCA test also revealed higher total score, factor executive function score, naming and orientation at day 60 than those measured at days 0 and 7 in psychotherapy group (P＜0. 05). However, in medication group, only factor orientation score in MMSE and factor executive function and orientation score were significantly higher at day 60 than those at days 0 and 7 (P＜0. 05). The psychotherapy group showed significantly decreased HAMD and SDS score as well as enhanced total score of MMSE and MoCA compared with that of medication group (P＜0.05). Conclusion: Psychotherapy helps to attenuate depression and cognitive impairment in patients with PD.关键词
帕金森病/心理干预/认知功能障碍/抑郁Key words
Parkinson's disease/ psychotherapy/ cognitive impairment/ depression分类
医药卫生引用本文复制引用
梅俊华,邵卫,周景芬,陈国华,笱玉兰,潘晓峰..心理干预辅助药物治疗帕金森病抑郁与认知障碍[J].神经损伤与功能重建,2011,6(2):118-122,5.
