湖南中医药大学学报2011，Vol.31Issue(1)：22-24,3.DOI:10.3969/j.issn.1674-070X.2011.01.006.022.03
雄性"肾阳虚"亚健康大鼠模型的研究
Study on sub-health model of male Kidney-yang deficiency in rats
摘要
Abstract
Objective To explore the sub-health model of male Kidney-yang deficiency in rats and look for a method for regulation of male Kidney-yang deficiency in human. Method Vitamin B4 was used to set up the sub-health rats model of male Kidney-yang deficiency, the level of anterior pituitary-testiculus axle hormone, the content of oxidative damage factors and anti -oxidative damage factors, the fine structure of testicle tissue were detected to measure histological baseness in sub-health condition. Result Compared with normal rats, the levels of FSH, LH, T and SOD were decreased(P＜0.05), and content of MDA was increased(P＜ 0.01). the seminiferous tubule structure of testicle tissue was neat but lumen was expanded. There were the part-fusing in sperm tail, spermatogenic cell-staging decreased, ranged abnormal and existed the vacuolus. Conclusion Vitamin B4 can be used to establish the sub-health model.关键词
肾阳虚/亚健康/维生素B4/大鼠Key words
Kidney-yang deficiency/ sub-health/ vitamin B4/ rats分类
医药卫生引用本文复制引用
李天禹,何清湖,卢芳国,刘朝圣,万胜..雄性"肾阳虚"亚健康大鼠模型的研究[J].湖南中医药大学学报,2011,31(1):22-24,3.基金项目
湖南省教育厅科学研究青年项目(08B057) （08B057）
湖南省研究生科研创新基金项目(CX2009B173). （CX2009B173）
