口腔颌面外科杂志2011,Vol.21Issue(1):30-33,4.DOI:10.3969/j.issn.1005-4979.2011.01.008
阿霉素神经干注射结合病变骨腔外科处理治疗原发性三叉神经痛的临床观察
Clinical Observation of Adriamycin Nerve-trunk Injection Combining with Surgical Management of Pathological Bone Cavity in Treating Primary Trigeminal Neuralgia
摘要
Abstract
Objective: To evaluate the clinical effects of adriamycin nerve-trunk injection combined with surgical management of pathological bone cavity in treating primary trigeminal neuralgia.Methods: 60 patients with primary trigeminal neuralgia were randomly divided into two groups: the treatment group and control group.The patients in treatment group accepted adriamycin nerve-trunk injection combined with surgical management of pathological bone cavity.The patients in control group were treated with carbamazepine.1 year after treatment, the patients were followed up.The pain score and clinical efficacy were compared and analyzed statistically between the two groups.Results: 29 people were followed up in the treatment group; 28 people were followed up in the control group.The rate of follow-up was more than 90%.The pain score of patients in treatment group was 2.38±l.90,and 4.07±2.00 in the control group.There was significant difference between two groups (t=-3.28,P<0.01).The total effective rate in treatment group was 93.10%,75% in the control group.There was significant difference between the two groups (x2=11.99,P<0.01).Conclusion:Adriamycin nerve-trunk injection combined with surgical management of pathological bone cavity is a simple and effective therapeutic method in treatment of primary trigeminal neuralgia.关键词
阿霉素/神经干注射/外科处理/原发性三叉神经痛Key words
Adriamycin/ nerve-trunk injection/ pathological bone cavity/ primary trigeminal neuralgia分类
医药卫生引用本文复制引用
雷荣昌,梁非照,王俊林..阿霉素神经干注射结合病变骨腔外科处理治疗原发性三叉神经痛的临床观察[J].口腔颌面外科杂志,2011,21(1):30-33,4.基金项目
柳州市科技局资助项目(2008031426) (2008031426)