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阿霉素神经干注射结合病变骨腔外科处理治疗原发性三叉神经痛的临床观察

雷荣昌 梁非照 王俊林

口腔颌面外科杂志2011,Vol.21Issue(1):30-33,4.
口腔颌面外科杂志2011,Vol.21Issue(1):30-33,4.DOI:10.3969/j.issn.1005-4979.2011.01.008

阿霉素神经干注射结合病变骨腔外科处理治疗原发性三叉神经痛的临床观察

Clinical Observation of Adriamycin Nerve-trunk Injection Combining with Surgical Management of Pathological Bone Cavity in Treating Primary Trigeminal Neuralgia

雷荣昌 1梁非照 1王俊林1

作者信息

  • 1. 广西医科大学第五附属医院口腔科,广西柳州,545006
  • 折叠

摘要

Abstract

Objective: To evaluate the clinical effects of adriamycin nerve-trunk injection combined with surgical management of pathological bone cavity in treating primary trigeminal neuralgia.Methods: 60 patients with primary trigeminal neuralgia were randomly divided into two groups: the treatment group and control group.The patients in treatment group accepted adriamycin nerve-trunk injection combined with surgical management of pathological bone cavity.The patients in control group were treated with carbamazepine.1 year after treatment, the patients were followed up.The pain score and clinical efficacy were compared and analyzed statistically between the two groups.Results: 29 people were followed up in the treatment group; 28 people were followed up in the control group.The rate of follow-up was more than 90%.The pain score of patients in treatment group was 2.38±l.90,and 4.07±2.00 in the control group.There was significant difference between two groups (t=-3.28,P<0.01).The total effective rate in treatment group was 93.10%,75% in the control group.There was significant difference between the two groups (x2=11.99,P<0.01).Conclusion:Adriamycin nerve-trunk injection combined with surgical management of pathological bone cavity is a simple and effective therapeutic method in treatment of primary trigeminal neuralgia.

关键词

阿霉素/神经干注射/外科处理/原发性三叉神经痛

Key words

Adriamycin/ nerve-trunk injection/ pathological bone cavity/ primary trigeminal neuralgia

分类

医药卫生

引用本文复制引用

雷荣昌,梁非照,王俊林..阿霉素神经干注射结合病变骨腔外科处理治疗原发性三叉神经痛的临床观察[J].口腔颌面外科杂志,2011,21(1):30-33,4.

基金项目

柳州市科技局资助项目(2008031426) (2008031426)

口腔颌面外科杂志

OACSTPCD

1005-4979

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