山东医药2011，Vol.51Issue(9)：4-6,3.
交感神经皮肤反应和R-R间期变化率对诊断格林巴利综合征自主神经损害的意义
Application of sympathetic skin response and R-R interval variation in Guillain-Barre syndrome
摘要
Abstract
Objective To evaluate possible autonomic nervous system (ANS) dysfunction in Guillain-Barre syndrome patients by the sympathetic skin response (SSR) and the heart rate (R-R) interval variation (RRIV) measurements and discuss the value in diagnosis by SSR and RRIV in GBS. Methods We studied 26 cases of Guillain-Barre syndrome patients and 30 cases of age-matched healthy subjects, recorded the SSR latency and amplitude of hands and feet, also recorded the RRIV when people at normal breathing and deep breathing. Results ①Between the GBS group and the control group, the SSR latency was no significant difference ( P ＞ 0.05 ), the amplitude of the difference was statistically significant ( P ＜0.05). ②Compared the GBS group to the control group, RRIV at normal breathing and deep breathing were statistically significant (P＜0. 05). ③RRIV abnormal rate and SSR abnormal rate in GBS group were no statistical significance ( P ＞ 0. 05 ). Compared with symptomatic GBS, SSR and RRIV were statistically significantly ( P ＜ 0. 05 ). ④ Compared the AIDP to the AMASN, SSR and RRIV were no statistically significant (P＞0.05). Conclusions SSR and RRIV can be used as the objective electrophysiologieal indicators, and can find the under clinical autonomic neuropathy in GBS.关键词
交感神经皮肤反应/R-R 间期变化率/格林巴利综合征/自主神经通路分类
医药卫生引用本文复制引用
孙瑶,谢炳,姚源蓉..交感神经皮肤反应和R-R间期变化率对诊断格林巴利综合征自主神经损害的意义[J].山东医药,2011,51(9):4-6,3.基金项目
国家自然科学基金资助项目(30800356) （30800356）
天津市自然科学基金资助项目(07JCYBJC16200) （07JCYBJC16200）
教育部留学回国人员科研启动基金(教外司留[2008]890号) （教外司留[2008]890号）
天津医科大学总医院引进人才科研启动基金. （）
